Samejima, K., P. Villa & W.C. Earnshaw. (1999). Role of factors downstream of caspases in nuclear disassembly during apoptotic execution. Phil. Trans. Roy. Soc. Lond. B., 354: 1591-1599. PMID: 10582245; PMC1692664; DOI: 10.1098/rstb.1999.0503 FREE ARTICLE
Earnshaw, W.C. (1999). Apoptosis: A cellular poison cupboard. Nature 397: 387-389. PMID: 9989401; DOI: 10.1038/17015 FREE ARTICLE
Kaufmann, S.H., L.M. Martins, P.W. Mesner Jr., T.J. Kottke and W.C. Earnshaw. (1999). Methods Used to Study Protease Activation During Apoptosis. In: Apoptosis in Neurobiology (Hannun, Y.A., and Boustany, R-M, eds.). CRC Press, New York. pp. 205-232. DOI: https://doi.org/10.1201/9780367801946 BOOK
Halappanavar, S.S., LeRhun, Y., Mounir, S., Martins, L.M., Huot, J., Earnshaw, W.C. and G.M. Shah. (1999). Survival and proliferation of cells expressing caspase-uncleavable poly(ADP-ribose) polymerase in response to death-inducing DNA damage by an alkylating agent. J. Biol. Chem. 274: 37097-37104. PMID: 10601269; DOI: 10.1074/jbc.274.52.37097; FREE ARTICLE
Everett, R.D., W.C. Earnshaw, A.F. Pluta, T. Sternsdorf, A.M. Ainsztein, M. Carmena, S. Ruchaud, W.-L. Hsu & A. Orr. (1999). A dynamic connection between centromeres and ND10 proteins. J. Cell Sci. 112: 3443-3454. PMID: 10504293; DOI: unknown; FREE ARTICLE
Mesner, P.W. Jr., K.C. Bible, L.M. Martins, T.J. Kottke, S.M. Srinivasula, P.A. Svingen, T. Chilcote, G. Basi, J. Tung, S.Krajewski, J.C. Reed, E.S. Alnemri, W.C. Earnshaw and S.H. Kaufmann. (1999). Characterization of Caspase Processing and Activation in HL-60 Cell Cytosol Under Cell-Free Conditions: Nucleotide Requirement and Inhibitor Profile. J. Biol. Chem. 274: 22635-22645. PMID: 10428844; DOI: 10.1074/jbc.274.32.22635; FREE ARTICLE
Kottke, T.J., A.L. Blajeski, L.M. Martins, P.W. Mesner, Jr., D.K. Armstrong, W. Devereaux, W.C. Earnshaw, N.E. Davidson, and S.H. Kaufmann (1999) Comparison of Paclitaxel-, 5-Fluoro-2′-deoxyuridine- and EpidermalGrowth Factor-Induced Apoptosis: Evidence for EGF-Induced Anoikis. J. Biol. Chem. 274: 15927-15936. PMID: 10336499; DOI: 10.1074/jbc.274.22.15927; FREE ARTICLE
Tyler-Smith, C. G. Gimelli, S. Giglio, G. Floridia, A. Pandya, G. Terzoli, P.E. Warburton, W.C. Earnshaw & O. Zuffardi. (1999). Transmission of a fully functional human neocentromere through three generations. Am. J. Hum. Genet. 64:1440-1444. PMID: 10205277; PMC1377882; DOI: 10.1086/302380; FREE ARTICLE
Gisselsson, D., M. Höglund, F. Mertens, B. Johansson, P.D. Cin, H. Van den Berghe, W.C. Earnshaw, F. Mitelman & N. Mandahl. (1999) The structure and dynamics of ring chromosomes in human neoplastic and non-neoplastic cells. Hum. Genet. 104: 315-325. PMID: 10369161; DOI: 10.1007/s004390050960; ARTICLE
Everett, R.D., W.C. Earnshaw, J. Findlay & P. Lomonte. (1999). Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110. The EMBO J. 18: 1526-1538. PMID: 10075924; PMC1171241; DOI: 10.1093/emboj/18.6.1526; FREE ARTICLE
Samejima, K. P.A. Svingen, G.S. Basi, T. Kottke, P.W. Mesner,Jr., L. Stewart, F. Durrieu, G.G. Poirier, E.S. Alnemri, J.J. Champoux, S.H. Kaufmann & W.C. Earnshaw. (1999). Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis. J. Biol. Chem. 274, 4335-4340. PMID: 9933635; DOI: 10.1074/jbc.274.7.4335; FREE ARTICLE
Savoian, M., W.C. Earnshaw, A. Khodjakov & C.L. Rieder. (1999). Cleavage Furrows Formed Between Centrosomes Lacking An Intervening Spindle and Chromosomes Contain Microtubule Bundles, INCENP, and CHO1 but Not CENP-E. Mol. Biol. Cell 10: 297-311. PMID: 9950678; PMC25170; DOI: unknown; FREE ARTICLE
Earnshaw, W.C. (1998). Introduction. Papers from the 4th international workshop on chromosome segregation and aneuploidy, Porto 1998. Chromosoma 107: 351. PMID: 9914365 DOI: 10.1007/s004120050317 ARTICLE
Earnshaw, W.C. (1998). The Centromere by K.H. Andy Choo. Book review. Am. J. Hum. Genet. 63: 290-291. DOI: https://doi.org/10.1086/301914; FREE ARTICLE
Earnshaw, W.C. and A. Ainsztein. (1998). Biology in Pictures: Chromosomal Passengers. Curr. Biol. 8: R403. DOI: https://doi.org/10.1016/S0960-9822(98)70260-X; FREE ARTICLE
Earnshaw, W.C. (1998). Worthy of your undivided attention: review of Cytokinesis in Animal Cells by R. Rappaport. Trends Cell Biol. 8: 91-92. DOI: https://doi.org/10.1016/S0962-8924(98)80021-4; ARTICLE
Craig, J.M., W.C. Earnshaw & P. Vagnarelli. (1998). Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression. Exp. Cell Res. 246: 249-262. PMID: 9925740; DOI: 10.1006/excr.1998.4278; ARTICLE
Earnshaw, W.C., L.M. Martins & S.H. Kaufmann. (1999). Mammalian caspases: Structure, activation, substrates and functions during apoptosis. Annu. Rev. Biochem., 68: 383-424. PMID: 110872455; DOI: 10.1146/annurev.biochem.68.1.383; FREE ARTICLE
Ainsztein, A.M., S.E. Kandels-Lewis, A.M. Mackay & W.C. Earnshaw. (1998). INCENP centromere and spindle targeting: Identification of essential conserved motifs and involvement of heterochromatin protein HP1. J. Cell Biol., 143: 1763-1774. PMID: 9864353; PMC2175214; DOI: 10.1083/jcb.143.7.1763; FREE ARTICLE
Jablonski, S. A., Chan, G. K. T., Cooke, C. A., Earnshaw, W. C. and T.J. Yen. (1998). hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis. Chromosoma 107: 386-396. PMID: 9914370; DOI: 10.1007/s004120050322; ARTICLE
Martins, L.M., T.J. Kottke, S.H. Kaufmann and W.C. Earnshaw (1998). Phosphorylated forms of activated caspases are present in cytosol from HL-60 cells during etoposide-induced apoptosis. Blood 92: 3042-3049. PMID: 9787137; DOI: unknown; FREE ARTICLE
Samejima, K., S.Toné, T.J. Kottke, M. Enari,H. Sakahira, C.A. Cooke, F. Durrieu, L.M. Martins, S. Nagata, S.H. Kaufmann and W.C. Earnshaw. (1998). Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution. J. Cell Biol. 143: 225-239. 9763434; PMC2132820; DOI: 10.1083/jcb.143.1.225; FREE ARTICLE
Samejima, K. and W.C. Earnshaw (1998). ICAD/DFF regulator of apoptotic nuclease is nuclear Exp. Cell Res. 243: 453-459. PMID: 9743604; DOI: unknown; ARTICLE
Olie, R.A., F. Durrieu, S. Cornillon, G. Loughran, J. Gross, W.C. Earnshaw and P. Golstein. (1998). Apparent caspase independence of programmed cell death in Dictyostelium. Curr. Biol. 8: 955-958. PMID: 9742396; DOI: 10.1016/S0960-9822(98)70395-1; FREE ARTICLE
Pluta, A.F., W.C. Earnshaw, I.G. Goldberg (1998) Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death. J. Cell Sci. 111: 2029-2041. PMID: 9645950; DOI: unknown; FREE ARTICLE
Lamond, A.I. & W.C. Earnshaw. (1998). Structure and Function in the Nucleus. Science 280: 547-553. PMID: 9554838; DOI: 10.1126/science.280.5363.547; ARTICLE
Mackay, A.M., A.M. Ainsztein, D.M. Eckley & W.C. Earnshaw. (1998). A dominant mutant of INCENP, a chromosomal protein, disrupts prometaphase congression and cytokinesis. J. Cell Biol. 140: 991-1002. PMID: 9490714; PMC2132686; DOI: 10.1083/jcb.140.5.991; FREE ARTICLE
Clem, R.J., E.H.-Y. Cheng, C.L. Karp, D.G. Kirsch, K. Ueno, A. Takahashi, M.B. Kastan, D.E. Griffin, W.C. Earnshaw, M.A. Veliuona and J.M. Hardwick. (1998). Modulation of cell death by Bcl-xL through caspase interaction. Proc. Nat. Acad. Sci. (USA) 95: 554-559. PMID: 9435230; PMC18458; DOI: 10.1073/pnas.95.2.554; FREE ARTICLE
Takahashi, A., Alnemri, E. S., Fernandes-Alnemri, T., Lazebnik, Y. A., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H. and W.C. Earnshaw. (1997). Biochemical dissection of nuclear events in apoptosis. In Cell Cycle Regulation (ed. R. R. Ruffolo Jr, G. Poste and B.W. Metcalf), Harwood Academic Publishers, The Netherlands. pp. 131-149. CHAPTER PREVIEW
Villa, P., S.H. Kaufmann & W.C. Earnshaw. (1997). Caspases and caspase inhibitors. Trends Biochem. Sci., 22: 388-393. PMID: 9357314; DOI: 10.1016/S0968-0004(97)01107-9 ARTICLE
Takahashi, A. and W.C. Earnshaw. (1997). In vitro systems for the study of apoptosis. In Advances In Pharmacology : Apoptosis: Pharmacological Implications and Therapeutic Opportunities (ed. S. H. Kaufmann), 41: 89-106. San Diego: Academic Press.
Warburton, P.E. & W.C. Earnshaw. (1997). Untangling the role of DNA topoisomerase II in mitotic chromosome structure and function. BioEssays 19: 97-99. PMID: 9046238; DOI: 10.1002/bies.950190203 ARTICLE
Cooke, C.A., B. Schaar, T.J. Yen & W.C. Earnshaw. (1997). Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase. Chromosoma 106: 446-455. PMID: 9391217; DOI: 10.1007/s004120050266; ARTICLE
Martins, L.M., P.W. Mesner, T.J. Kottke, G.S. Basi, S. Sinha, J.S. Tung, P.A. Svingen, B.J. Madden, A. Takahashi, D.J. McCormick, W.C. Earnshaw and S.H. Kaufmann. (1997). Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis. Blood 90: 4283-4296. PMID: 9373239; DOI: https://doi.org/10.1182/blood.V90.11.4283 FREE ARTICLE
Warburton, P.E., C.A. Cooke, S. Bourassa, O. Vafa, B.A.Sullivan, G. Stetten, G. Gimelli, D. Warburton, C. Tyler-Smith, K.F. Sullivan, G.G. Poirier & W.C. Earnshaw. (1997). Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr. Biol., 7: 901-904. PMID: 9382805; DOI: 10.1016/S0960-9822(06)00382-4; FREE ARTICLE
Fisher, A.M., Al-Gazali, L., Pramathan, T., Quaife, R., Cockwell, A.E., Barber, J.C.K., Earnshaw, W.C., Axelman, J., Migeon, B. & Tyler-Smith, C. (1997). Centromere inactivation in a dicentric human Y;21 translocation chromosome. Chromosoma 106: 199-206. PMID: 9254721; DOI: 10.1007/s004120050240; FREE ARTICLE
Depinet, T.W., Zackowski, J.L., Earnshaw, W.C., Kaffe, S., Sekhon, G.S., Stallard, R., Sullivan, B.A., Vance, G.H., Van Dyke, D.L., Willard, H.F., Zinn, A.B. & Schwartz, S. (1997). Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA. Hum. Mol. Genet. 6: 1195-1204. PMID: 9259264; DOI: 10.1093/hmg/6.8.1195; FREE ARTICLE
Eischen, C.M., Kottke, T.J., Martins, L.M., Basi, G.S., Tung, J.S., Earnshaw, W.C., Leibson, P.J. & S.H. Kaufmann. (1997). Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood, 90: 935-943. PMID: 9242521; DOI: https://doi.org/10.1182/blood.V90.3.935; FREE ARTICLE
D’Amours, D., P.J. Duriez, K. Orth, R.G. Shah, V.M. Dixit, W.C. Earnshaw, E.S. Alnemri & G.G. Poirier. (1997). Purification of the death substrate poly(ADP-ribose) polymerase. Anal. Biochem. 249: 106-108. PMID: 9193717; DOI: 10.1006/abio.1997.2153; ARTICLE
Eckley, D. M., Ainsztein, A.M., Mackay, A.M., Goldberg, I.G., and W.C. Earnshaw. (1997). Chromosomal proteins and cytokinesis: Patterns of cleavage furrow formation and Inner Centromere Protein positioning in mitotic heterokaryons and mid-anaphase cells. J. Cell Biol., 136:1169 – 1183. 9087435; PMC2132506; DOI: 10.1083/jcb.136.6.1169; FREE ARTICLE
Martins, L.M., Kottke,T., Mesner, P.W., Basi, G.S., Sinha, S., Frigon, N. Jr., Tatar, E., Tung, J.S., Bryant, Takahashi, A., Svingen, P.A., Madden, B.J., McCormick, D.J., W.C. Earnshaw, W.C. & S.H. Kaufmann. (1997). Activation of multiple Interleukin-1b converting enzyme homologues in cytosol and nuclei of HL-60 human leukemia cells during etoposide-induced apoptosis. J. Biol. Chem. 272: 7421-7430. PMID: 9054443; DOI: 10.1074/jbc.272.11.7421; FREE ARTICLE
Martins, L.M. & W.C. Earnshaw. (1997). Apoptosis: alive and kicking in 1997. Trends Cell Biol. 7: 111-114. PMID: 17708919; DOI: 10.1016/S0962-8924(96)10053-2; ARTICLE
Takahashi, A., Goldschmidt-Clermont, P.J., Alnemri, E.S., Fernandes-Alnemri, T., Yoshizawa-Kumagaya, K., Nakajima, K., Sasada, M., Poirier, G.G. & W.C. Earnshaw (1997). Inhibition of ICE-related proteases (caspases) and nuclear apoptosis by phenylarsine oxide. Exp. Cell Res. 231:123 – 131. PMID: 9056419; DOI: 10.1006/excr.1996.3459; ARTICLE
Takahashi, A. & W.C. Earnshaw. (1996). ICE-related proteases in apoptosis. Curr. Op. Genet. Dev. 6: 50-55. PMID: 8791488; DOI: 10.1016/S0959-437X(96) ARTICLE
Takahashi, A. Musy, P.-Y., Martins, L.M. Poirier, G.G. Turner, P.C., Moyer, R.W. & and W.C. Earnshaw (1996). CrmA/SPI-2 inhibition of an endogenous ICE-related protease responsible for lamin A cleavage and apoptotic nuclear fragmentation. J. Biol. Chem. 271: 32487-32490. PMID: 8955067; DOI: 10.1074/jbc.271.51.32487; FREE ARTICLE
Froelich, C.J., Hanna, W.L., Poirier, G.G., Duriez, P.J., D’Amours, D., Salvesen, G.S., Alnemri, E.S., Earnshaw, W.C. & G.M. Shah. (1996). Granzyme B/perforin mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89 kDa apoptotic fragment and less abundant 64 kDa fragment. Biochem. Biophys. Res. Com. , 227: 658-665. PMID: 8885990; DOI: 10.1006/bbrc.1996.1565; ARTICLE
Saitoh, H., C.A. Cooke, W.H. Burgess, W.C. Earnshaw & M. Dasso (1996). Direct and indirect association of the small GTPase Ran with nuclear pore proteins and soluble transport factors: Studies in Xenopus laevis egg extracts. Mol. Biol. Cell, 7: 1319-1334. PMID: 8885229, PMC275984; DOI: 0.1091/mbc.7.9.1319; FREE ARTICLE
Goldberg, I.G., H. Sawhney, A.F. Pluta, P.E. Warburton & W.C. Earnshaw (1996). Surprising deficiency of CENP-B binding sites in African green monkey a-satellite DNA: Implications for CENP-B function at centromeres. Mol. Cell. Biol. 16: 5156-5168. PMID: 8756673; PMC231516; DOI: 10.1128/mcb.16.9.5156; FREE ARTICLE
Takahashi, A., E.S. Alnemri, Y.A. Lazebnik, T. Fernandes-Alnemri, G. Litwack, R.D. Moir, R.D. Goldman, G.G. Poirier, S.H. Kaufmann & W.C. Earnshaw (1996). Cleavage of lamin A by Mch2a but not CPP32: Multiple ICE-related proteases with distinct substrate recognition properties are active in apoptosis. Proc. Nat. Acad. Sci. (USA) 93: 8395-8400. PMID: 8710882; PMC38682; DOI: 10.1073/pnas.93.16.8395; FREE ARTICLE
Pluta, A. F. and W.C. Earnshaw (1996) Specific interaction between human kinetochore protein CENP-C and a nucleolar transcriptional regulator. J. Biol. Chem. 271: 18767-18774. PMID: 8702533; DOI: 10.1074/jbc.271.31.18767; FREE ARTICLE
Yang, C.H., J. Tomkiel, H. Saitoh, D.H. Johnson & W.C. Earnshaw (1996). Identification of overlapping DNA-binding and centromere-targeting domains in the human kinetochore protein CENP-C. Mol. Cell. Biol. 16: 3576-3586. PMID: 8668174; PMC231353; DOI: 10.1128/mcb.16.7.3576; FREE ARTICLE
Wordeman, L., W.C. Earnshaw & R.L. Bernat (1996). Disruption of CENP antigen function perturbs dynein anchoring to the mitotic kinetochore. Chromosoma, 104: 551-560. PMID: 8662248; DOI: 10.1007/BF00352295; ARTICLE
Malek,S. N. , C. H. Yang, W. C. Earnshaw, C. A. Kozak & S. Desiderio (1996) 150(TSP), a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains. J. Biol. Chem. 271: 6952-6962. PMID: 8636124; DOI: 10.1074/jbc.271.12.6952; FREE ARTICLE
Lazebnik, Y.A., A. Takahashi, G.G Poirier, S.H. Kaufmann & W.C. Earnshaw. (1995). Characterization of the execution phase of apoptosis in vitro using extracts from condemned-phase cells. J. Cell Sci. Suppl. 19: 41-49. PMID: 8655646 DOI: 10.1242/jcs.1995.supplement_19.6 FREE ARTICLE
Earnshaw, W.C. (1995) Nuclear Changes in Apoptosis. Curr. Opin. Cell Biol. 7: 337-343. PMID: 7662363; DOI: 10.1016/0955-0674(95)80088-3 ARTICLE
Fernandes-Alnemri, T., A. Takahashi, R. Armstrong, J. Krebs, L. Fritz, K.J. Tomaselli, L. Wang, Z. Yu, C.M. Croce, G. Salveson, W.C. Earnshaw, G. Litwack and E. S. Alnemri. (1995). Mch3, a novel human apoptotic cysteine protease related to CPP32. Cancer Res. 55: 6045-6052. PMID: 8521391; DOI: unknown; FREE ARTICLE
Pluta, A., A.M. Mackay, A.M. Ainsztein, I.G. Goldberg & W.C. Earnshaw. (1995). The centromere: Hub of chromosomal activities. Science 270: 1591-1594. PMID: 7502067; DOI: 10.1126/science.270.5242.1591; ARTICLE
Lazebnik, Y.A., A. Takahashi, R.D. Moir, R.D. Goldman, G.G Poirier, S.H. Kaufmann & W.C. Earnshaw (1995). Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc. Nat. Acad. Sci. (USA) 92: 9042-9046. PMID: 7568069; PMC40920; DOI: 10.1073/pnas.92.20.9042; FREE ARTICLE
Saitoh, N., I.G. Goldberg and W.C. Earnshaw. (1995). The SMC proteins and the coming of age of the chromosome scaffold hypothesis. BioEssays 17: 759-766. PMID: 8763828; DOI:10.1002/bies.950170905; ARTICLE
Earnshaw, W.C. (1995) Apoptosis: Lessons from in vitro systems. Trends Cell Biol. 5: 217-220. PMID: 14732117; DOI: 10.1016/S0962-8924(00)89006-6; ARTICLE
Whyte, J., W.C. Earnshaw, J.J. Champoux, L.H. Parker, L.J. Stewart, N.D. Hall & N.J. McHugh (1995). Detection of anti-topoisomerase-I antibodies using a full length human topoisomerase-I recombinant protein purified from a baculovirus expression system. Clin. Exp. Immunol., 100: 214-218. 7743657; PMC1534349; DOI: 10.1111/j.1365-2249.1995.tb03655.x; FREE ARTICLE
Whyte, J., E. Soriano, W.C. Earnshaw, N.J. McHugh. (1995). Frequency of autoantibodies to a major epitope on the carboxyl-terminal fragment of CENP-B in patients with autoimmune-disease. Brit. J. Rheumatol. 34: 407-412 PMID: 7788167; DOI: 10.1093/rheumatology/34.5.407; ARTICLE
Tugendreich, S., J. Tomkiel, W. Earnshaw & P. Hieter (1995). The CDC27Hs protein is essential for the metaphase to anaphase transition and co-localizes with the CDC16Hs protein to the centrosome and mitotic spindle. Cell, 81: 261-268. PMID: 7736578; DOI: 10.1016/0092-8674(95)90336-4; FREE ARTICLE
Vázquez-Abad, D., C.A. Russell, S.M. Cusick, W.C. Earnshaw & N.F. Rothfield. (1995). Longitudinal study of anticentromere and antitopoisomerase-I isotypes. Clin. Immunol. Immunopath. 3: 257-270. PMID: 7859416; DOI: 10.1006/clin.1995.1038; ARTICLE
Page, S.L., W.C. Earnshaw, K.H.A. Choo & L.G. Shaffer. (1995). Further evidence that CENP-C is a necessary component of active centromeres: studies of a dic(X;15) with simultaneous immunofluorescence and FISH. Hum. Mol. Genet. 4: 289-294. PMID: 7757082; DOI: 10.1093/hmg/4.2.289; ARTICLE
Mackay, A.M. & W.C. Earnshaw. (1994). The INCENPs: Structural and functional analysis of a family of chromosome passenger proteins. Cold Spring Harbor Symp. Quant. Biol., 58: 697-706. PMID: 7956086 DOI: 10.1101/sqb.1993.058.01.077 ARTICLE
Earnshaw, W.C. (1994). Structure and molecular biology of the kinetochore. in Microtubules, J.S. Hyams C. Lloyd, eds. Wiley-Liss, Inc., New York. pp. 393-412.
Saitoh, N., Goldberg, I., Wood, E. & W.C. Earnshaw. (1994). ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure. J. Cell Biol. 127: 303-318. PMID: 7929577; DOI: 10.1083/jcb.127.2.303; FREE ARTICLE
Lazebnik, Y.A., Kaufmann, S.H., Desnoyers, S., Poirier, G.G. & W.C. Earnshaw. (1994). Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371: 346-347. PMID: 8090205; DOI: 10.1038/371346a0; ARTICLE
Earnshaw, W.C. & A.M. Mackay. (1994). The role of non-histone proteins in the chromosomal events of mitosis. The FASEB J. 8: 947-956. PMID: 8088460; DOI: 10.1096/fasebj.8.12.8088460; FREE ARTICLE
Earnshaw, W.C. & A.F. Pluta. (1994). Mitosis. BioEssays 16: 639-643. PMID: 7980489; DOI: 10.1002/bies.950160908; ARTICLE
Tomkiel, J.E., C.A. Cooke, H. Saitoh, R.L. Bernat & W.C. Earnshaw. (1994). CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. J. Cell Biol., 125: 531-545. PMID: 8175879; DOI: 10.1083/jcb.125.3.531; FREE ARTICLE
Vázquez-Abad, D., S. Wallace, J.-L. Senécal, F. Joyal, A. Roussin, W.C. Earnshaw & N.F. Rothfield. (1994). Anticentromere autoantibodies. Evaluation of an ELISA using recombinant fusion protein CENP-B as antigen. Arthritis Rheum. 37: 248-252. PMID: 8129780; DOI: 10.1002/art.1780370214; FREE ARTICLE
Tomkiel, J.E. & W.C. Earnshaw. (1993). Structure of the mammalian centromere. in Chromosome Segregation and Anneuploidy. B.K. Vig, ed. Springer-Verlag, Berlin. pp. 13-29. DOI: https://doi.org/10.1007/978-3-642-84938-1_2; PREVIEW
Earnshaw, W.C., H. Saitoh, J.E. Tomkiel, C.A. Cooke, R.L. Bernat, H. Ratrie, M. Maurer & N.F. Rothfield. (1993). Molecular cloning and characterization of human centromeric autoantigen CENP-C: a component of the inner kinetochore plate. in Chromosomes Today. vol. 11, A.T. Sumner & A.C. Chandley, eds. Chapman & Hall, London. pp. 23-34. DOI: https://doi.org/10.1007/978-94-011-1510-0_2; PREVIEW
Mackay, A.M., D.M. Eckley, C. Chue & W.C. Earnshaw. (1993). Molecular analysis of the INCENPs: Separate domains are required for association with microtubules during interphase and with the central spindle during anaphase. J. Cell Biol. 123: 373-385. PMID: 8408220; DOI: 10.1083/jcb.123.2.373; FREE ARTICLE
Lazebnik, Y.A., S. Cole, C.A. Cooke, W.G. Nelson & W.C. Earnshaw. (1993). Nuclear events of apoptosis in vitro in cell-free mitotic extracts: A model system for analysis of the active phase of apoptosis. J. Cell Biol. 123: 7-22. PMID: 8408207; DOI: 10.1083/jcb.123.1.7; (Featured in From the Archive, The Journal of Cell Biology 173, 150-151 (2006).) FREE ARTICLE
Cooke, C.A., D. P. Bazett-Jones, W.C. Earnshaw & J.B. Rattner. (1993). Mapping DNA within the mammalian kinetochore. J. Cell Biol. 120: 1083-1091. PMID: 7679671; DOI: 10.1083/jcb.120.5.1083; FREE ARTICLE
Saunders, W.S., C. Chue, M. Goebl, C. Craig, R.F. Clark, J.A. Powers, J.C. Eissenberg, S.C. R. Elgin, N.F. Rothfield & W.C. Earnshaw. (1993). Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anticentromere autoantibodies with anti-chromo specificity. J. Cell Sci. 104: 573-582. PMID: 8505380; DOI: unknown; FREE ARTICLE
Jabs, E.W., C.M. Tuckmuller, G.J. Anhalt, W.C. Earnshaw, R.A. Wise & F. Wigley. (1993). Cytogenetic survey in systemic sclerosis – correlation of aneuploidy with the presence of anticentromere antibodies. Cytogenet. Cell Genet. 63: 169-175. PMID: 8387418; DOI: 10.1159/000133527; FREE ARTICLE
Earnshaw, W.C., I. Goldberg, A.F. Pluta, N.F. Rothfield, H. Saitoh, W.S. Saunders & J.E. Tomkiel. (1992). Molecular characterization of centromere-associated autoantigens. in Scleroderma International Symposium – Current Topics In Scleroderma. M. Maeda & I Ogawa, eds. Seino Print Co., Gifu City, JAPAN. pp. 87-106.
Earnshaw, W.C. & J.E. Tomkiel. (1992). Centromere and kinetochore structure. Curr. Opin. Cell Biol. 4: 86-93. PMID: 1558757 DOI: 10.1016/0955-0674(92)90063-I ARTICLE
Saitoh, H., Tomkiel, J., Cooke, C.A., Ratrie, H., Maurer, M., Rothfield, N.F. & W.C. Earnshaw. (1992). CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70:115-125. PMID: 1339310; DOI: 10.1016/0092-8674(92)90538-N; ARTICLE
Pluta, A.F., N. Saitoh, I. Goldberg & W.C. Earnshaw. (1992). Identification of a subdomain of CENP-B that is necessary and sufficient for localization to the human centromere. J. Cell Biol. 116:1081-1093. PMID: 1740467; DOI: 10.1083/jcb.116.5.1081; FREE ARTICLE
Earnshaw, W.C., Bernat, R.L., Cooke, C.A., & N.F. Rothfield. (1991) The role of the centromere/ kinetochore in cell cycle control. Cold Spring Harbor Symp. Quant. Biol., 56: 675-685. PMID: 1819515; DOI: 10.1101/sqb.1991.056.01.076 ARTICLE
Earnshaw, W.C. & J.B. Rattner. (1991). The use of autoantibodies in the study of nuclear and chromosomal organization. in Methods In Cell Biology vol. 35, B.A. Hamkalo & S.C. Elgin, eds. Academic Press, San Diego. pp. 135-175. PMID: 1723479; DOI: https://doi.org/10.1016/S0091-679X(08)60572-5; ARTICLE
Earnshaw, W.C. (1991). Large scale chromosome structure and organization. Curr. Opin. Struct. Biol. 1: 237-244. DOI: https://doi.org/10.1016/0959-440X(91)90068-5 ARTICLE
Saunders, W.S., Cooke, C.A. & W.C. Earnshaw. (1991). Compartmentalization within the nucleus: Discovery of a novel subnuclear region. J. Cell Biol. 115: 919-931. PMID: 1955462; DOI: 10.1083/jcb.115.4.919; FREE ARTICLE
Bernat, R.L., Delannoy, M.R., Rothfield, N.F. & W.C. Earnshaw. (1991). Disruption of centromere assembly during interphase inhibits kinetochore morphogenesis and function in mitosis. Cell, 66: 1229-1238. PMID: 1913807; DOI: 10.1016/0092-8674(91)90045-Z; ARTICLE
Earnshaw, W.C. (1991). When is a centromere not a kinetochore? J. Cell Sci. 99: 1-4. PMID: 1757494; DOI: unknown; FREE ARTICLE
Yen, T.J., Compton, D.A., Wise, D., Zinkowski, R.P., Brinkley, B.R., Earnshaw, W.C. & D.W. Cleveland. (1991). CENP-E, a novel human centromere associated protein required for progression from metaphase to anaphase. The EMBO J. 10: 1245-1254. PMID: 2022189; PMC452779; DOI: unknown; FREE ARTICLE
Earnshaw, W.C. & C.A. Cooke. (1991). Analysis of the distribution of the INCENPs throughout mitosis reveals the existence of a pathway of structural changes in the chromosomes during metaphase and early events in cleavage furrow formation. J. Cell Sci. 98: 443-461. PMID: 1860899; DOI: unknown; FREE ARTICLE
Earnshaw, W.C. & R.L. Bernat. (1990). Chromosomal passengers: Towards an integrated view of mitosis. Chromosoma, 100:139-146. PMID: 2040201; DOI: 10.1007/BF00337241; ARTICLE
Hildebrandt, S., Noell, G.S., Vázquez-Abad, D., Earnshaw, W.C., Zanetti, M. and N.F. Rothfield. (1991). Idiotypic analysis of human anti-topoisomerase-I autoantibodies. Autoimmunity 10: 41-48. PMID: 1660312; DOI: 10.3109/08916939108997146; ARTICLE
Hildebrandt, S., E.S. Weiner, W.C. Earnshaw, M. Zanetti, N.F. Rothfield. (1991). Idiotypic Analysis Of Human Anticentromere Autoantibodies. Autoimmunity 9: 131-140 PMID: 1657226; DOI: 10.3109/08916939109006749; ARTICLE
Weiner, E.S., Hildebrandt, S., Senecal, J.-L., Daniels, L., Noell, S., Joyal, F., Roussin, A., Earnshaw, W., N.F. Rothfield. (1991). Prognostic significance of anticentromere antibodies and anti-topoisomerase I antibodies in Raynaud’s disease: A prospective study. Arthritis Rheum. 34:68-77. PMID: 1845841; DOI: 10.1002/art.1780340111; FREE ARTICLE
Earnshaw, W.C. & M.M.S. Heck.(1990). Topoisomerase II in mitotic chromosome structure. in The Eukaryotic Nucleus: Molecular Biochemistry and Macromolecular Assemblies. P. Strauss and S. Wilson, eds. Telford Press. pp. 639-657. BOOK
Wevrick, R., Earnshaw, W.C., Howard-Peebles, P.N. & H. Willard. (1990). Partial deletion of alpha satellite DNA associated with reduced amounts of the centromere protein CENP-B in a mitotically stable human chromosome rearrangement. Mol. Cell. Biol. 10:6348-6355. PMID: 2247061; PMC362913; DOI: 10.1128/mcb.10.12.6374; FREE ARTICLE
Wood, E.R. & W.C. Earnshaw. (1990). Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II. J. Cell Biol. 111: 2839-2850. PMID: 2176652; DOI: 10.1083/jcb.111.6.2839; FREE ARTICLE
Hildebrandt, S., Wiener, E.S., Senécal, J.-L., Noell, S., Earnshaw, W.C. & N.F. Rothfield. (1990). Autoantibodies to topoisomerase I (Scl-70): Analysis by gel diffusion, immunoblot, and enzyme-linked immunosorbent assay. Clin. Immunol. Immunopath. 57: 399-410. PMID: 2173985; DOI: 10.1016/0090-1229(90)90114-6; ARTICLE
Bernat, R.L., Borisy, G.G., Rothfield, N.F. & W.C. Earnshaw. (1990). Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis. J. Cell Biol. , 111:1519-1533. PMID: 2211824; DOI: 10.1083/jcb.111.4.1519; FREE ARTICLE
D’Arpa, P. P., Cleveland, D.W., White-Cooper, H., Rothfield, N.F. & W.C. Earnshaw. (1990). Use of molecular cloning methods to map the distribution of epitopes on topoisomerase I (Scl-70) recognized by sera of scleroderma patients. Arthritis Rheum. , 33: 1501-1511. PMID: 1699543; DOI: 10.1002/art.1780331007; FREE ARTICLE
Pluta, A.F., Cooke, C.A. & W.C. Earnshaw. (1990). Structure of the human centromere at metaphase. Trends Bioch. Sci. 15: 181-185. PMID: 2193435; DOI: 10.1016/0968-0004(90)90158-8; ARTICLE
Cooke, C.A., Bernat, R.L. & W.C. Earnshaw. (1990). CENP-B: A major human centromere protein located beneath the kinetochore. J. Cell Biol. 110: 1475-1488. PMID: 2335558; DOI: 10.1083/jcb.110.5.1475; FREE ARTICLE
Hildebrandt, S., Wiener, E.S., Senécal, J.-L., Noell, S., Daniels, L., Earnshaw, W.C. & N.F. Rothfield. (1990). The IgG, IgM and IgA isotypes of anti-topoisomerase I and anti-centromere autoantibodies. Arthritis Rheum. , 33: 724-727. PMID: 2161233; DOI: 10.1002/art.1780330515; FREE ARTICLE
Moens, P.B. & W.C. Earnshaw. (1990). Anti-topoisomerase II recognizes meiotic chromosome cores. Chromosoma 98:317-322. PMID: 2558860; DOI: 10.1007/BF00292383; ARTICLE