Forming chromosomes
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What are the principal structural and biochemical events that drive chromosome formation as cells enter mitosis?
Coating chromosomes
![Projects 211 earnshaw lab projects](https://earnshawlab.com/wp-content/uploads/2020/04/cropped-earnshaw-em.png)
How do nucleolar proteins and RNAs assemble the mitotic chromosome periphery compartment and is this important?
Segregating chromosomes
![Projects 224 Projects 223](https://earnshawlab.com/wp-content/uploads/2020/05/Bergmann-HAC-photo-1024x619.png)
How is centromere chromatin assembled, organised and disassembled during mitosis on an endogenous vertebrate chromosome and during human artificial chromosome (HAC) formation?
![Projects 239 Ruchaud CPC Metaphase, Anaphase](https://earnshawlab.com/wp-content/uploads/2020/04/ruchaud-cpc-metaphase-anaphase-earnshaw-lab.jpg)
Controlling the process
![Projects 239 Ruchaud CPC Metaphase, Anaphase](https://earnshawlab.com/wp-content/uploads/2020/04/ruchaud-cpc-metaphase-anaphase-earnshaw-lab.jpg)
How do mitotic kinases, including Cdk1 and Aurora B in the Chromosomal Passenger Complex (CPC), regulate events during synchronous entry and exit from mitosis?
Explaining Cell Biology
An attempt to bring the beauty and wonders of the world of Cell Biology alive to a new generation of undergraduates and more advanced science and medical students
![Projects 266 Projects 265](https://earnshawlab.com/wp-content/uploads/2022/11/Book-Project-screenshot-1024x790.png)
Image: Fernanda Cisneros-Soberanis, Graham Johnson, Thomas Brown