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Bill Earnshaw
- Cell Biology
Projects
Publications
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Gallery
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Home
Bill Earnshaw
- Cell Biology
Projects
Publications
Team
Gallery
- Videos
Protocols
Public Engagement
Contact

Gallery

FORMING CHROMOSOMES

All-Models-were-correct-JB-Rattner-E-DUPRaw-Bill-Earnshaw-�-Anton-Golobdorodko

Another-Demonstration-of-perfect-register-in-correlative-light-and-EM-of-RPE1-metaphase-cell-Dan-Booth

Chromatin-22peeling22-reveals-the-radial-loops-in-a-human-chromosome-Bill-Earnshaw-1982

Chromosome-morphology-is-aberrant-after-SMC2-depletion-but-mitotic-chromatin-volume-is-near-normal-Kumiko-Samejima-Dan-Boothg

Condensin-I-forms-80-kb-loops-nested-within-400-kb-loops-previously-generated-by-helical-condensin-II

Demonstrating-perfect-register-in-correlative-light-and-EM-of-RPE1-metaphase-cell-Dan-Booth

Diagram-and-gel-showing-isolation-of-chromosome-scaffolds-Bill-Earnshaw

Distinct-roles-for-condensin-I-and-condensin-II-in-mitotic-chromosome-organisation

Dramatic-Hi-C-changes-during-synchronous-mitotic-entry-a-helix-of-loops-produces-a-second-diagonal-in-the-heat-maps-Kumiko-Samejima-Johan-Gibcus

Effects-of-condensin-mutants-on-mitotic-chromosome-formation-Kumiko-Samejima

Hi-resolution-analysis-of-mitotic-entry-in-wild-type-DT40-Cdk1-as-cells-Kumiko-Samejima

KIF4A-is-a-kinesin-that-also-is-required-for-mitotic-chromosome-structure-Kumiko-Samejima

MCCP-multiclassifier-combinatorial-proteomics-classifier-II-Shinya-Ohta

MCCP-multiclassifier-combinatorial-proteomics-mapping-of-protein-classesShinya-Ohta-Jimi-Carlo-Bukowski-Wills

Mitotic-chromosome-with-loops-of-30-nm-fiber-Bill-Earnshaw-1982

Overlaying-individual-chromosomes-in-3d-in-correlative-light-and-EM-of-RPE1-metaphase-cell-Dan-Booth

Synchronous-mitotic-entry-of-DT40-Cdk1-as-cells-after-1NM-PP1-washout-Kumiko-Samejima

Synchronous-mitotic-entry-of-HeLa-Cdk1-as-cells-after-1NM-PP1-washout-anaphase-Jan-Ruppert

Synchronous-mitotic-entry-of-HeLa-Cdk1-as-cells-after-1NM-PP1-washout-early-metaphase-Jan-Ruppert

Synchronous-mitotic-entry-of-HeLa-Cdk1-as-cells-after-1NM-PP1-washout-G2-Jan-Ruppert

Synchronous-mitotic-entry-of-HeLa-Cdk1-as-cells-after-1NM-PP1-washout-metaphase-Jan-Ruppert

Synchronous-mitotic-entry-of-HeLa-Cdk1-as-cells-after-1NM-PP1-washout-prometaphase-Jan-Ruppert

Synchronous-mitotic-entry-of-HeLa-Cdk1-as-cells-after-1NM-PP1-washout-prophase-Jan-Ruppert

Synchronous-mitotic-entry-of-HeLa-Cdk1-as-cells-after-1NM-PP1-washout-Jan-Ruppert.png

COATING CHROMOSOMES

Correlative-Light-and-EM-image-showing-Ki-67-knockdown-causes-dispersal-of-the-chromosome-periphery-Dan-Booth

Disruption-of-the-chromosome-periphery-after-Ki-67-RNAi-Paola-Vagnarelli-Dan-Booth

Ki-67-RNAi-disrupts-the-mitotic-chromosome-periphery-Paola-Vagnarelli

RPE1 metaphase cell segmented and modeled after CLEM by Dan Booth

SEGREGATING CHROMOSOMES

ACA-and-tubulin-staining-of-anaphase-with-prototype-confocal-microscope-Bill-Earnshaw

ACA-confocal-anaphase-adj

ACA-injection-disrupts-kinetochores-Becky-Bernat

ACA-stained-chromosome-spread-with-dic15-Bill-Earnshaw-Mimi-Jabs

Bill-used-antibodies-from-a-scleroderma-patient-to-identify-the-first-kinetochore-proteins-in-any-species

CENP-C-is-in-the-inner-kinetochore-plate-immunoEM-by-Carol-Cooke

CENP-E-is-in-the-kinetochore-corona-immunoEM-by-Carol-Cooke

CENPs-A-B-C-the-first-kinetochore-proteins-in-any-species-Bill-Earnshaw-Naomi-Rothfield

Centromeres-are-transcribed-in-mitosis-Oscar-Molina

Depletion-of-condensin-causes-centromeric-chromatin-to-become-excessively-stretchy-Susana-Ribeiro

DIcentric-chromosome-stained-for-CENP-B-and-CENP-C-kinetochore-Paola-Vagnarelli

Dicentric-X-chromosome-first-evidence-for-epigenetic-reguolation-of-kinetochore-assembly-Bill-Earnshaw-Barbara-Migeon

Discovery-of-the-first-human-neocentromere-in-1989-the-clinicians-would-not-publish-it-Bill-Earnshaw-and-Jolene-Witkowski

Expression-of-CLASP-microtubule-binding-fragment-gives-fireworks-separate-channels-Helder-Maiato

Kinetochores-can-tolerate-moderate-transcription-but-too-much-kills-them-Jan-Bergmann

Localisation-of-CENP-A-relative-to-other-centromerekinetochore-markers-Peter-Warburton

Loss-of-cohesion-at-an-inactive-centromere-stained-for-CENP-B-CENP-C-Paola-Vagnarelli

Massive-rearrangements-of-120-kb-HAC-seeding-DNA-occur-early-during-HAC-formation.-Established-HACs-are-stable-Elisa-Pesenti

Needle-microinjection-of-ACA-into-HeLa-cells-causes-them-to-become-monsters-Becky-Bernat

Needle-microinjection-of-ACA-into-HeLa-cells-disrupts-kinetochores-Becky-Bernat-and-Mike-Delanoy

Needle-microinjection-of-anti-CENP-C-into-HeLa-cells-makes-small-kinetochores-John-Tomkiel-and-Mike-Delanoy

Phase-contrast-of-anaphase-cell-with-centromeres-stained-with-colloidal-gold-Carol-Cooke

CONTROLLING THE PROCESS

Anaphase-in-Drosophila-embryo-stained-for-INCENP-Mar-Carmena

Aurora-B-and-the-CPC-are-located-in-the-inner-centromere-Paola-Vagnarelli

DIsruption-of-mitosis-after-Borealin-siRNA-Ana-Carvalho

Distribution-of-the-CPC-chromosomal-passenger-complex-at-Metaphase-Anaphase-Sandrine-Ruchaud

INCENP-and-Aurora-B-are-required-for-H3S10-phosphorylation-Helder-Maiato-Richard-Adams

INCENP-STD-motif-reveals-CPC-role-in-triggering-membrane-furrowing-in-vertebrates-Sandrine-Ruchaud

Survivin-conditional-knockout-phenotype-in-DT40-cells-Ana-Carvalho-Zuojun-Yue

Survivin-is-a-component-of-the-chromosomal-passenger-complex-CPC-Ana-Carvalho-Sally-Wheatley

PUBLIC ENGAGEMENT

Joel-Katz-drawing-of-chromatin-packing

Charles-mitosis-gallery

Prophase-cell-stained-for-CENP-E-red-microtubules-green-and-DNA-blue-deconvolved-image-from-DeltaVision-microscope-Bill-Earnshaw

Prometaphase-cell-stained-for-CENP-E-red-microtubules-green-and-DNA-blue-deconvolved-image-from-DeltaVision-microscope-Bill-Earnshaw

Metaphase-cell-stained-for-CENP-E-red-microtubules-green-and-DNA-blue-deconvolved-image-from-DeltaVision-microscope-Bill-Earnshaw

Late-anaphase-cell-stained-for-CENP-E-red-microtubules-green-and-DNA-blue-deconvolved-image-from-DeltaVision-microscope-Bill-Earnshaw.jpg

Cytokinesis-cell-stained-for-CENP-E-red-microtubules-green-and-DNA-blue-deconvolved-image-from-DeltaVision-microscope-Bill-Earnshaw.jpg

Skye-Is-a-Kinetochore-Ana-Carvalho-Bill-Earnshaw-Skye

Expression-of-CLASP-microtubule-binding-fragment-gives-fireworks-Helder-Maiato

What-did-this-hand-from-a-Raynauds-Patient-tell-us-about-kinetochores

How-to-microinject-heLa-cells-and-keep-them-happy-Alastair-Mackay-note-this-image-has-been-manipulated

Bills-cartoon-of-how-PALM-microscopy-works

DT40-cell-on-steroids

Where-Bill-was-when-the-Nepal-Earthquake-hit-altitude-4600-m-between-Dingboche-and-Chukkung

Bill lecturing at KAIST (Korean Advanced Institute for Science and Technology) in Daejeon, Korea March 2023

Bill answers questions at KAIST (Daejeon, Korea, March 2023)

Bill with his hosts at KAIST (Daejeon, Korea, March 2023)

PEOPLE

The-chromosome-formation-team-May-2020-copy

In-Norman-Cave-resting-with-visitor-Joel-Rosenbaum

Margarete-Heck-in-Hamilton-Cave

BIll-Carol-Cooke-in-1989

Hank-Ratrie-in-Norman-cave

Bill, Vadim, Kumeiko and Tim Hunt in Vladivostok 2019

The-Group-2005

The Group 2007

The-Group-2010

The-Group-2001

The-Group-2018

The-Group-2019

Hank-Ratrie-running-the-Big-Falls-River-at-dusk-1989

2020 Christmas get together

The-team-who-made-the-first-synthetic-human-artificial-chromosome

The-Hi-C-and-chromosome-formation-team-clockwise-from-top-left-Sameer-Abraham-Anton-Golobdorodko-Leonid-Mirny-Job-Dekker-Johan-Gibcue-Kumiko-Samejima-Bill-Earnshaw-

Naomi-Rothfield-and-her-team-Her-antibody-bank-identified-the-first-kinetochore-proteins-in-any-species

Bill-on-Morraine-above-Everest-Base-Camp-2013

Bill-in-the-Lake-District-2013

BIll-drawn-by-Joel-Katz-in-1985

Bill-above-Annapurna-Base-Camp-2011

university of edinburgh

Earnshaw Lab

Centre for Cell Biology

University of Edinburgh
Michael Swann Building
Max Born Crescent
Edinburgh, EH9 3BF
SCOTLAND, UK

Cell Biology, 4th edition
a textbook (Elsevier)

By Thomas D. Pollard,
William C Earnshaw,
Jennifer Lippincott-Schwartz
and Graham Johnson

To learn more, visit here

© 2020 W.C. Earnshaw Lab - Website Credits